Q: We deployed the CDO Patch and it messed up the "send as" permission on all the mailboxes. Lots of TREO issues on Monday morning we had to go back and adjust permissions to get it to work. What are we doing wrong? A: Please take a look at KB article
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Read the complete post at http://blogs.technet.com/dst2007/archive/2007/03/01/the-cdo-patch-messed-up-send-as-permission-on-mailboxes-what-are-we-doing-wrong.aspx